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April 17, 2012
Lancet Oncology Study
Study shows significant side effect reduction with HIFU to treat prostate cancer... more >


Sky News, April 17, 2012
Prostate Cancer Treatment 'Reduces Side Effects'
A high-powered beam of ultrasound can destroy prostate cancer without causing the serious side effects... more >


Urology Times, May 1, 2012
Data show low morbidity of HIFU in short-term trials
Technique appears safe, but evaluation of efficacy awaits longer-term data... more >

The Sonablate® 500

The Sonablate is a minimally invasive medical device designed to treat prostate cancer with HIFU energy. By way of a transrectal probe, the Sonablate captures real-time images of the prostate gland allowing the treating physician to create a customised treatment plan for each patient. The physician then uses the Sonablate to deliver the ultrasound energy to extremely small target sites, or focal points, throughout the prostate gland.

Features of the Sonablate system include:

  • Only HIFU device for treating prostate cancer that does not require an advance surgical procedure (known as a TURP) in order to achieve effective results for enlarged prostates up to 40 grams.
  • Treating physicians are in control of the Sonablate’s power settings and can adjust them based on real-time feedback after delivery of the ultrasound energy by using an innovative software feature known as TCM, or tissue change monitoring.
  • Each lesion produced by the Sonablate’s energy delivery is 10-12mm in length, smaller than other prostate cancer HIFU devices, which allows for greater precision and conformity in small, critical spaces around the gland.
  • The Sonablate has real-time, three-dimensional imaging, enabling the physician to detect even slight movement of the device or gland, which could compromise treatment.
  • The Sonablate uses a fully integrated probe with two transducers, one to image the prostate gland and the other to treat with HIFU.

Visually Guided HIFU

Tissue Change Monitoring Software (TCM)
TCM is a unique software designed for the Sonablate that monitors real-time tissue changes during HIFU therapy for the treatment of malignant and benign prostate disease. TCM provides feedback on the treatment in real-time so that the surgeon knows exactly what is happening to the prostate tissue during HIFU. TCM has the potential to reduce side effects for patients because physicians can tailor the amount of heat used for each individual patient.



How does TCM work?

A radio frequency (RF) signal is sent to a treatment site prior to delivery of HIFU and then another signal is sent after delivery of HIFU in the same treatment site. TCM calculates the change that took place and displays it on-screen. TCM quantifies tissue changes based on a comparison of radio frequency (RF) ultrasound pulse-echo signals at each treatment sites.

Click here to download the TCM brochure.



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